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Multiple IVF Failures Causes and Treatment
IVF is termed to have failed repeatedly when there is failure to achieve pregnancy even after transfer of at least three or four good quality embryos in fresh or frozen cycles in women under 40 years of age. While most of the ART (Assisted Reproductive Technology) clinics report an implantation rate of 40-60%, the exact incidence in lacking due to the difference in definition of implantation.
Repeated IVF failure can be attributed to quite a few reasons. These can be embryo related, parental chromosomal abnormalities which leads to abnormal embryo formation or oocyte aneuploidies dur to advanced maternal age.

Causes of Multiple IVF Failure-
- Chromosomal Abnormality
- Thin endometrium
- High sperm DFI (DNA Fragmentation Index)
- Immunological factors
- Autoantibodies
- Intra-Uterine adhesions (scar tissue)
- Defective endometrial receptivity
- High BMI
- Defective endometrial receptivity
- High BMI
- Polyps
- Fibroids Adenomyosis
- Presence of Hydrosalpinx
- Congenital abnormalities in uterus
- Advanced maternal age
- Medical conditions in mother
It is necessary to investigate a couple with recurrent IVF failure .For diagnosing the cause of repeated IVF failure uterine evaluation through Hysteroscopy is sometimes very useful.
Endometrial Receptive Array (ERA) is used to evaluate the receptivity of the uterus. This helps in determining the time when the uterus is completely ready to receive the embryo and the procedure can be scheduled accordingly.
The couple must maintain a healthy lifestyle along with proper diet, yoga, exercise and refrain from smoking, alcohol and habit-forming drugs during the course of treatment. Better results can be achieved by following the proper guidelines and instructions by the doctor and selecting a genuine IVF centre.
Recommended Recommended Procedures after Repeated IVF Failures can be -
FAQ’s
What is the Next Step After Multiple IVF Failure?
There are multiple factors of multiple IVF failures. Also we always do not find a cause .One need to review the patient assessment and depending upon the evaluation choosing an advanced infertility treatment . Also the factors like IVF centre selection, their embryology team and laboratories also plays an important role in IVF success.
How many times can IVF fail?
Before achieving pregancy IVF failure occurs due to several reasons, the number of IVF cycle attempts and failures vary for every couple.
How can I increase my IVF success rate?
IVF cycle is a critical process and preparing your body physically and emotionally for the procedure can be challenging.
The following tips can be helpful for increasing your IVF success rates:
Lead a healthy lifestyle Work on your diet Take the required supplements Avoid stress

Fertility and Diet : How Nutrition Impacts Your Chances of Conception
A well-balanced, healthy diet rich in fruits, vegetables, whole grains, and lean protein, while avoiding processed foods and excessive sugar, can benefit both men and women’s fertility and can help when a couple is trying to conceive.